Council members of Lincolnshire County Council have approved a devolution deal for the area which will see the establishment of the Greater Lincolnshire Mayoral Combined County.
The deal is set to bring increased local decision-making and funding, with an extra £24m per year for the next 30 years.
A public consultation received around 4,000 responses from the 1.1 million residents of Greater Lincolnshire.
North Lincolnshire and North East Lincolnshire councils will also hold votes on whether to proceed.
Council leader Martin Hill said: ‘All three councils see this as a great opportunity to be the masters of our own destiny and not be left behind when it comes to government investment.
‘I’m really grateful to all those who took part in the consultation. There was some incredibly useful feedback that was given including innovative ideas that can be taken forward as part of the work that will now be done.’